Subchronic, reproductive, and maternal toxicity studies with tertiary butyl acetate (TBAC).

The Acute and Subchronic Effects of Methyl Tertiary Butyl Ether on Some Fertility Indices in The Male Rats

Abstract Background and Objectives: Methyl-tertiary butyl ether (MTBE) is one of the fuel oxygenated additive that is used to reduce the environmental pollution resulting from engine combustion. This study was carried out to evaluate the acute (1 day) and subchronic (30 days) effects of MTBE on some fertility indices in the male rats. Methods: In this study, under two separate experiments (acut...

LC50 Determination of tert-Butyl Acetate using a Nose Only Inhalation Exposure in Rats

tert-Butyl acetate (TBAc) is an organic solvent, which is commonly used in architectural coatings and industrial solvents. It has recently been exempted from the definition of a volatile organic compound (VOC) by the Air Resources Board (ARB) . Since the use of TBAc as a substitute for other VOCs has increased, thus its potential risk in humans has also increased. However, its inhalation toxici...

Updated evaluation (Oct. 2015) of the genetic toxicology of tert-butanol (TBA) and tert-Butyl acetate (TBAC)

The overall response to TBA and TBAC in genetic toxicology assays is very weak to negative. There are only three papers that are relevant to TBA with purported positive responses. These results are far out-numbered by negative results in the mouse lymphoma assay, Chinese hamster ovary assessment for SCEs, aberrations and micronuclei, and negative responses in Salmonella TA 98, 100, 104, 1535, a...

Short communication-Survey of Methyl Tertiary Butyl Ether (MTBE) toxicity using bioassay on Daphnia magna

EVALUATION OF THE ACUTE AND SUBCHRONIC TOXICITY OF Aster tataricus L. F.

BACKGROUND Aster tataricus L. f. is used as a traditional Chinese drug to relieve cough and asthma symptoms and to eliminate phlegm. However, Aster tataricus L. f. possesses toxicity, and little systematic research has been conducted on its toxic effects in the laboratory. METHODS AND MATERIALS The acute group was administered 75% alcohol extract of Aster tataricus L. f. in a single dose. A s...